Risk factors for post-endoscopic retrograde pancreatography pancreatitis in malignant extrahepatic biliary obstruction: a retrospective single-center study

Background. Decompression interventions under the endoscopic retrograde cholangiopancreatography (ERCP) is method of choice in malignant extrahepatic biliary obstruction (MEHBO). Acute pancreatitis most common complication ERCP. Many studies have been performed to identify risk factors for post-ERCP (PEP). However, these works general include analysis ERCP patients with various causes without subdividing obstruction.
 Purpose.The aim this study was determine PEP MEHBO.
 Materials and Methods. A retrospective 100 cases MEHBO done. 2 patients, 14 had hyperamylasemia (HA). The following were analyzed: gender, age, level MEHBO, main pancreatic duct (MPD), total bilirubin level, history papillosphincterotomy (EPST), periampullary diverticulum, successful ERCP, primary selective cannulation, catheterization and/or contrast injection into MPD, Precut EPST, decompression.
 Results discussion. Univariate showed that associated an at proximal middle third hepaticocholedochus (p = 0.004) absence MPD 0.022); female gender 0.012), < 0.001), 0.040) are or (HA); 0.024), (p=0.006), 0.035), decompression HA. Multivariate regression that, HA as well HA, 0.005; p 0.001; 0.001, respectively) 0.022; 0.008, respectively). Female a factor 0.011; 0.028, respectively), 0.04). Conclusion. Development depends on localization tumor involvement pancreas. obstruction.